ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
FDA analysis of 40-years of antibacterial development: Dheman et al.
Public meeting on the LPAD Pathway: Post-meeting thoughts (wonkish)
The hunt for oral antibiotics: Beyond Lipinski’s Rule of Five
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
FDA and EMA regulatory updates / Fireside chat during the 4th AMR Conference
Global survey of novel antibiotic reimbursement models / PASTEUR Act introduced to US House
Assessing antibiotic value: DTR, fire extinguishers, and a view from Australia
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
UK to expand NHS Subscription Pilot! Consultation Period launches
Non-traditional antibiotics: A pipeline review and an analysis of key development challenges
COVID-19 and the Long-Term Trajectory of AMR Efforts: Wellcome Trust Deep Dive
Developing antibiotics for children: There are no easy answers
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet